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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f7e9d3f397d390491d79ba18d74b0dbec914edb4b6e201d1e82984461d86db' 
  AND token = 'XBwGI1Nl+xVnCPVa6Oar7DGKldgDEGbmYhHGVGwRhsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}