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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb36f9f414cf97bab35d0eeae8c77e81eca540239732862292999b1776f0e3f' 
  AND token = 'X/ux/FvyEujFJ+nlNkIKnJxKqsW0nywOeOm22ffNkEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}