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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da17f9d19ce4a6196c267729de75594b2a7990d1f12731e8ea085d0df41d96a4' 
  AND token = 'RBp+/7k5n2tjwRmqKF0h+WnTgIcUldYiWDdvTFbEwBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}