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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50fcf207f82c20642c37d146003caec3c2fe59471f01adaf471d410532738b21' 
  AND token = 'x/z2qjDaLgB8lWVSo1gACnrhRj6sOxhyGSA2MjluOmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}