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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d901a0b6210f88ad41734a16a2dfcff1e504806a680d797a018b61ac3b442c3' 
  AND token = 'AsEsK/2p5ALKxvBv4m8LqD2aTT3iZJLr2g9oE+MKWe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}