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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '021100a55ffd4471c069c6d37ecc908f7d62a27e569be70050acdb22dd224bb8' 
  AND token = 'pExRWfaKZOUTZ5dLfs05+Ec7K4DL9jxr4iESRD3hipU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}