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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e048ef67c071f231939af5115ebf5442c14792f428472b33c3efbe7dd27422b0' 
  AND token = 'HxXarZR+JC5Uak3J+PhoLOO+pkokS15qcZCaGZPsgBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}