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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2289a9c3c8092e07766bf2940df4fa0e43536728d8eb470d13d6e2f8d050246' 
  AND token = '7fv8dv14iZ1snu4YPlmHRNbi6QMCcirbNisz/75/IrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}