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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ed10c0e94c76a8260a9d460a22e6396a3ecb1d113e2c2d03784a4cdcf592c2' 
  AND token = 'f6plOEgG/VDjuLHjTAxYCoDTcpPnkl3Ov1W79THMCVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}