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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9b0b4c2232928961d8302968b1e8e191bce21e5e1abbab8fee3427f2538422' 
  AND token = 'cgUjWTwitl3EbA1P5bwGfcd2kjiGw6T1PnQnZX7UJyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}