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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3173d9eec338744bc1ae1c3aec268a149b77dc4638a8ba43a0472764a18ad4b3' 
  AND token = 'Qh5xYAPh/4V5UzmWSQU0Dai9WgtYLMEYm7oeMaC/aa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}