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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f644dd49b04b13f2b19960d0b7e12f48a17d03e1f80ef8734c2ae78d567d7d52' 
  AND token = 'a8TeBwjjLEhtahwI9/5/7MhfqZVCtnbkXrBuqN6744I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}