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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd69d41ca42e5cd478ca8d9d9f8eb3341e6afba1027e321352f2d0f17e9a133' 
  AND token = 'kA6UdrOFdN9SJ4laWdoI9RPTRHLHrKAkqTDYguC1yv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}