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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308d1291f77d14619cb8a9c2a33223dd8cccb632dccced7994e97ed411b1b52c' 
  AND token = 'pu7WEgOFuOKYClZ2TAzwi39PhY+3KZZf6F56yWWRh1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}