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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c78d33eb4343465be2bd9b9c519bad418547c2bbdacde69191225127287e85' 
  AND token = 'MAH3rOL2f5tzT9Dj9OwujbDCnXdBgQKd/OFyawqcHSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}