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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43c2ec1cea8ff28c98cc5d7849465b04dffe14d588a7701e4140833508486a0' 
  AND token = 'L2kOdBHQ5O849UwtH3ca7oXseU9zuIxzp+t+0jSxOhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}