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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0761e5fc8368953bbf0c694146932c68916c38ce11b4a6895c85b8fcbbdf78cb' 
  AND token = 'tWw9rAasgCRRS9oQ/8PK2jFfS3jRfFK/1a8OoCNO//A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}