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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41d8ad7dcecbe2c84cae1e2570b64526b0edad615dccfd9d3c03c9661ff222f' 
  AND token = 'yVa0UJ/z6Cik7lhkUxlu/I1AtH4tYnRBeQ5TTGu4sis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}