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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0da910ad588665720ed458233366e302fd688667ecd51d45e72977a423583b2' 
  AND token = 'I6RabMsyIl4x0pV212XlHrPoSlMbfFOsNK9NqCh0Px4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}