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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561bab4e5f0b4efe2c20b31f093d6475338a91e135addca707305df5d3eb69e6' 
  AND token = 'EvIoRBFFDq7/F+V5CNPJgc1LHbjk6VQQMsRASQ6QiTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}