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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4914f44462604a36993c69133641dbbd43780e249a6302aa6265dfb6e0967d6' 
  AND token = 'bMAP4rLQKAc0mlk3rnE2VNPtDEjlOXhE3m4y+B+hJEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}