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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5450d45fa0b0be56d1d71e46957e195ef37c1f2f710f954ee721aa05fab63071' 
  AND token = 'eIim0fyz0x8uHH6sEInpixn4QuOjf02okOgkiVR9FPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}