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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd590f2391613f28d238c36c6c264e994242b87c429dc6d9dfc53ae5422d2f54' 
  AND token = 'PxciMCBhFmdCOd/J0TRLfE92eGJSva0OZmHyvqlz8T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}