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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a808d2ed61c0d134872d3fbc7a3d520014027971d1d7ed93bed8496c2905bf3' 
  AND token = '1tuWV0PGfvhcWPj2xm27aQtnn5WYni096I5wtK1FbmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}