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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc0331b0815b1200a0130d677096db4b508c32289fbaaee39710e279284c9bfa' 
  AND token = 'A8qs4fMTtZHmewZ6C7t6CW1nD8xjfIkC17zoDQCbnWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}