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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cc3214fd4b507eb4df8dc6e3ea059055ac5ca09b4934033ac268789581a9ca' 
  AND token = 'gpxNEosbW628Todp3M68+CODSs2vVqjlE0wtOQ+c37w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}