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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6b72c9c587255822f59106e26f29957aaad8a9d3765ab2a99224d8ccd2e8d2' 
  AND token = 'anaj/VBANf3URQBlI1kMdhfca9phNx1L7xUc9ov1G00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}