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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5eac18b78298b28cc942fa7be2405b8a72ca22c92a214402acebccbffea133' 
  AND token = 'NtjNfvbMutWQA2EqoLNctLfb66ghhYKMZLS9WsGR7uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}