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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f79bf0a491163ba157c0dbee7c9d6031b70be40a1dae09370a3f780efa790b' 
  AND token = 'a5Ss/XdEasd2CBQbaGFA8/j0lVVV7qvuy/NIEHw8Y70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}