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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628062735bae57e4e681fb4376e4da1721129a028fe729aca347a307436b7aa6' 
  AND token = 'CVs07vJ59irftMRety5w0RX0lgccTrelowPLxr7vLOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}