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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680647800fdf0523a17bba6bda4243b553b33d41e138047ab469eded3bcb4b37' 
  AND token = '3M6NddWb9at/qYRQhY3/mQFscGDgsOVXL8kI8v1ljjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}