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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd3898ef783483ed2301840c71e52880c0f1e95d728a4ad7b985c1abba8d319' 
  AND token = '2aqESjJdFP/gmdPaIhUoUWy2lVVTAY34nKpqMeXzTBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}