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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d72c45d150d04efdf04db72aadfbae3a7b3f22d228b81465ac24c542ebb09de' 
  AND token = 'Qso0GAQ1OZXeud147M8t7q6P9N/IEGYoWhVJG3M5G1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}