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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a276d572e379e63f92fab946fb2526f50ab847bc8a53e9d9d2612baead7448a' 
  AND token = '4Bvh4+kh5b+GQlWetz7rqjlbs7DurphtYxukWBnaTc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}