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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324e818f9c21293d64a45fdd7b2c20ce56a4015d0c6460e548e5e0ab31d4ea95' 
  AND token = '330V3H3m6VOHdIcvcceLkMrh43y07BimTwOnpT4BQaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}