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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef80099f92a4ef145a991fca2f331f49417a19b1956c1c23f17c964ee9e76710' 
  AND token = 'eSSREx2QellGI2gFGgUO2nNTHO6joZRC4NTMM//5H1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}