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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd456bd53a2b08c2ab7c74d46bbce7b64a83ee137d0e0ada323b169883f47ad9a' 
  AND token = 'M1+ojUGiOL0XBcdE/cBBLxpH9wqP/3MlrcBR0/vD/6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}