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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42193142828baaa1f3b113d3d6f819bdf9272b5825f8975c177b9871b5fc3d0' 
  AND token = 'NmBoBANqKTsGzSloX26gpYlRnRXUCjLGkbdAfBQAc4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}