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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2186c8a7bda835b07a81fce035ccaf1f468aa85010b615143bf2f3c5a149b5da' 
  AND token = 'IK10Z/CIUqiazab5WbrH0b8g+jY30KEjO2dQW0NZkDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}