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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ad1d47cb45d7f85887fa7f31c236fa70d384c083be009b8b7d529d83ac0765' 
  AND token = 'DrvZMJu34IC9Mq5432P04EMeg5uz3kuwNVjXJ83DKzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}