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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b368af126951267b366c0456a901b10dbc0d16d7c9206c344c9b702a2647755' 
  AND token = 'aiVnv3n0ir5ZuI8LfmWRiYYS0vKpDY7aFbHuSXcqLhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}