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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35492cf77d9f12d6c7401f10e7055f14d9771c833bd2f38c4ad6492127e5ec6f' 
  AND token = 'cwxRdhTrs2HiEgYR1YpzHRw+3/wlSZiXfzQ9puuTx/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}