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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0599321fea7bbcf922b76f7f1b7e385f5be4a7e5be66d86c187b9d05030f1376' 
  AND token = 'gyRlbYkGkinuHGZ4Bc9VtNpNyWoxVQ4h9IqvX53C6kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}