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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80e07a59b60789b6171ec6902e732a3eb736ff9c8af3401b049438d7506c0b6' 
  AND token = 'vIS778+AwLKzrOjia1qFWJXRIFl3p+hfyARNM+FUnBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}