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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '348aea66b2b27aada1cbc6d1cc82f05c5b3aceba77ee161ba592dd81392b53ef' 
  AND token = 'Rfj7uufasaZOYnnoZySWH/Cl2qTokjpZy+AfTu5I6/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}