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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0d4969259875dcad6c9a6874b55df6a82fca1065fe3e9539edae733d2e8bd5' 
  AND token = 'NdRYDZ15JLRwKM0OnkpFd0n+oTpELIIw3yzyWoCEDLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}