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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2157d92193f21af1a459f9d28ebeb3dd991c0725312413719dd8ce627d178473' 
  AND token = 'Q4/rpmzn3KnYxNNApSejC641PswFd46oZ1TtjLmSjVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}