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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211a97446b9f9bd666d8da4e0717201bbb4d0aae9a7658efcc9385553975f385' 
  AND token = 'BS/qFpv95nmbPln1ZjKZ0MezLcAxyPNnrFoGA1xH0n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}