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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8ec39928b7c8e12662234d13c3add73f29e62a12cc2667d9bf0b2f9a5115a1' 
  AND token = 'Dnq9yRgTpSglTzunEwq6Phui4FYia8ShtFAf/RjZop0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}