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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f456d505ce22d88d93b4f34811d6e566e9475569eb8c216028b8ea2f79c6c648' 
  AND token = 'XUt8HjoZliqCbLAFlPO4xRHG+yJ80Sb+o5R37bue9Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}